Woven Hydrogel Based Biosensor

Andrew Basner; Erik Burton; Gauri Shetye; Karen Simon; Mark Weldon; Yan-Yeung Luk

Woven Hydrogel Based Biosensor

Andrew Basner (Inventor), Erik Burton (Inventor), Gauri Shetye (Inventor), Karen Simon (Inventor), Mark Weldon (Inventor), Yan-Yeung Luk (Inventor)

Research output: Patent

Abstract

A porous hydrogel sensor that is responsive to the presence of one or more target compounds in solution is synthesized based on demixing of certain molecules in the presence of a target compound. The porous hydrogel sensor may include fluorescently tagged antibodies that are noncovalently bound to the gel and then released in the presence of the target antigen. The porous hydrogel sensor may alternatively include dissolvable cross-links using polymerized antibody and antigen complexes so that, in the presence of the target antigen, the cross-links will be displaced and the hydrogel will dissolve.

Original language	English (US)
State	Published - Mar 24 2016

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title = "Woven Hydrogel Based Biosensor",

abstract = "A porous hydrogel sensor that is responsive to the presence of one or more target compounds in solution is synthesized based on demixing of certain molecules in the presence of a target compound. The porous hydrogel sensor may include fluorescently tagged antibodies that are noncovalently bound to the gel and then released in the presence of the target antigen. The porous hydrogel sensor may alternatively include dissolvable cross-links using polymerized antibody and antigen complexes so that, in the presence of the target antigen, the cross-links will be displaced and the hydrogel will dissolve.",

author = "Andrew Basner and Erik Burton and Gauri Shetye and Karen Simon and Mark Weldon and Yan-Yeung Luk",

year = "2016",

month = mar,

day = "24",

language = "English (US)",

type = "Patent",

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TY - PAT

T1 - Woven Hydrogel Based Biosensor

AU - Basner, Andrew

AU - Burton, Erik

AU - Shetye, Gauri

AU - Simon, Karen

AU - Weldon, Mark

AU - Luk, Yan-Yeung

PY - 2016/3/24

Y1 - 2016/3/24

N2 - A porous hydrogel sensor that is responsive to the presence of one or more target compounds in solution is synthesized based on demixing of certain molecules in the presence of a target compound. The porous hydrogel sensor may include fluorescently tagged antibodies that are noncovalently bound to the gel and then released in the presence of the target antigen. The porous hydrogel sensor may alternatively include dissolvable cross-links using polymerized antibody and antigen complexes so that, in the presence of the target antigen, the cross-links will be displaced and the hydrogel will dissolve.

AB - A porous hydrogel sensor that is responsive to the presence of one or more target compounds in solution is synthesized based on demixing of certain molecules in the presence of a target compound. The porous hydrogel sensor may include fluorescently tagged antibodies that are noncovalently bound to the gel and then released in the presence of the target antigen. The porous hydrogel sensor may alternatively include dissolvable cross-links using polymerized antibody and antigen complexes so that, in the presence of the target antigen, the cross-links will be displaced and the hydrogel will dissolve.

M3 - Patent

ER -

Woven Hydrogel Based Biosensor

Abstract

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