Abstract
In this issue of Structure, Buel et al. (2023) combined NMR data with AlphaFold2 to map out the interaction between the AZUL domain of ubiquitin ligase E6AP and UBQLN1/2 UBA. The authors demonstrated that this interaction enhances the self-association of the helix neighboring UBA and enables E6AP to localize to UBQLN2 droplets.
Original language | English (US) |
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Pages (from-to) | 369-371 |
Number of pages | 3 |
Journal | Structure |
Volume | 31 |
Issue number | 4 |
DOIs |
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State | Published - Apr 6 2023 |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology