Vascular and central hemodynamic changes following exercise-induced heat stress

Wesley K. Lefferts; Kevin S. Heffernan; Eric M. Hultquist; Patricia C. Fehling; Denise L. Smith

doi:10.1177/1358863X14566430

Vascular and central hemodynamic changes following exercise-induced heat stress

Wesley K. Lefferts, Kevin S. Heffernan, Eric M. Hultquist, Patricia C. Fehling, Denise L. Smith

Department of Exercise Science

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

This study examined the effects of moderate exercise-induced heat stress (EIHS) on vascular function, central hemodynamic load and indices of coronary perfusion. Vascular-hemodynamic measures were collected in 12 healthy men (aged 22±3 years) pre and post 100 minutes of moderate, intermittent exercise in two randomized conditions: heat stress (HS; wearing firefighter personal protective equipment (PPE)), and no heat stress (NHS; wearing a cooling shirt and equivalent PPE weight). Aortic blood pressure, reflected wave pressure (Pb), systolic (SPTI) and diastolic pressure time-integral (DPTI), and aortic stiffness were assessed before and after each condition. SPTI was significantly greater, and DPTI and Pb were significantly lower for HS-post compared to NHS-post (p<0.05). Pulse wave velocity was not different between conditions. In conclusion, EIHS does not affect aortic stiffness, but increases indices of myocardial work and reduces indices of coronary perfusion which may be related to chronotropic responses to EIHS. The mismatch between oxygen demand and oxygen supply may increase cardiac vulnerability to ischemia during strenuous work in the heat.

Original language	English (US)
Pages (from-to)	222-229
Number of pages	8
Journal	Vascular Medicine (United Kingdom)
Volume	20
Issue number	3
DOIs	https://doi.org/10.1177/1358863X14566430
State	Published - Jun 5 2015

Keywords

arterial stiffness
heat stress
personal protective equipment
pulse wave reflections
wave separation analysis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Vascular and central hemodynamic changes following exercise-induced heat stress",

abstract = "This study examined the effects of moderate exercise-induced heat stress (EIHS) on vascular function, central hemodynamic load and indices of coronary perfusion. Vascular-hemodynamic measures were collected in 12 healthy men (aged 22±3 years) pre and post 100 minutes of moderate, intermittent exercise in two randomized conditions: heat stress (HS; wearing firefighter personal protective equipment (PPE)), and no heat stress (NHS; wearing a cooling shirt and equivalent PPE weight). Aortic blood pressure, reflected wave pressure (Pb), systolic (SPTI) and diastolic pressure time-integral (DPTI), and aortic stiffness were assessed before and after each condition. SPTI was significantly greater, and DPTI and Pb were significantly lower for HS-post compared to NHS-post (p<0.05). Pulse wave velocity was not different between conditions. In conclusion, EIHS does not affect aortic stiffness, but increases indices of myocardial work and reduces indices of coronary perfusion which may be related to chronotropic responses to EIHS. The mismatch between oxygen demand and oxygen supply may increase cardiac vulnerability to ischemia during strenuous work in the heat.",

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note = "Funding Information: This study was supported by a research grant from the Department of Homeland Security through a Federal Emergency Management Agency Assistance to Firefighters Grant (EMW-2010-FP-01992, Smith, PI). Publisher Copyright: {\textcopyright} The Author(s) 2015. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.",

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AU - Smith, Denise L.

N1 - Funding Information: This study was supported by a research grant from the Department of Homeland Security through a Federal Emergency Management Agency Assistance to Firefighters Grant (EMW-2010-FP-01992, Smith, PI). Publisher Copyright: © The Author(s) 2015. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.

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N2 - This study examined the effects of moderate exercise-induced heat stress (EIHS) on vascular function, central hemodynamic load and indices of coronary perfusion. Vascular-hemodynamic measures were collected in 12 healthy men (aged 22±3 years) pre and post 100 minutes of moderate, intermittent exercise in two randomized conditions: heat stress (HS; wearing firefighter personal protective equipment (PPE)), and no heat stress (NHS; wearing a cooling shirt and equivalent PPE weight). Aortic blood pressure, reflected wave pressure (Pb), systolic (SPTI) and diastolic pressure time-integral (DPTI), and aortic stiffness were assessed before and after each condition. SPTI was significantly greater, and DPTI and Pb were significantly lower for HS-post compared to NHS-post (p<0.05). Pulse wave velocity was not different between conditions. In conclusion, EIHS does not affect aortic stiffness, but increases indices of myocardial work and reduces indices of coronary perfusion which may be related to chronotropic responses to EIHS. The mismatch between oxygen demand and oxygen supply may increase cardiac vulnerability to ischemia during strenuous work in the heat.

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Vascular and central hemodynamic changes following exercise-induced heat stress

Abstract

Keywords

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