Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes

Xiaoran Hu; Matthew J. Feeney; Ethan McIntosh; James Mullahoo; Feng Jia; Qiaobing Xu; Samuel W. Thomas

doi:10.1021/acsami.6b07366

Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes

Xiaoran Hu, Matthew J. Feeney, Ethan McIntosh, James Mullahoo, Feng Jia, Qiaobing Xu, Samuel W. Thomas

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.

Original language	English (US)
Pages (from-to)	23517-23522
Number of pages	6
Journal	ACS Applied Materials and Interfaces
Volume	8
Issue number	36
DOIs	https://doi.org/10.1021/acsami.6b07366
State	Published - Sep 14 2016
Externally published	Yes

Keywords

nanoparticles
nitrobenzyl
photodegradable
polyelectrolyte complex
triggered release

ASJC Scopus subject areas

General Materials Science

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10.1021/acsami.6b07366

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title = "Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes",

abstract = "Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.",

keywords = "nanoparticles, nitrobenzyl, photodegradable, polyelectrolyte complex, triggered release",

author = "Xiaoran Hu and Feeney, {Matthew J.} and Ethan McIntosh and James Mullahoo and Feng Jia and Qiaobing Xu and Thomas, {Samuel W.}",

note = "Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

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doi = "10.1021/acsami.6b07366",

language = "English (US)",

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T1 - Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes

AU - Hu, Xiaoran

AU - Feeney, Matthew J.

AU - McIntosh, Ethan

AU - Mullahoo, James

AU - Jia, Feng

AU - Xu, Qiaobing

AU - Thomas, Samuel W.

PY - 2016/9/14

Y1 - 2016/9/14

N2 - Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.

AB - Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.

KW - nanoparticles

KW - nitrobenzyl

KW - photodegradable

KW - polyelectrolyte complex

KW - triggered release

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ER -

Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes

Abstract

Keywords

ASJC Scopus subject areas

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