Trajectories of maternal depressive symptoms over her child's life span: Relation to adrenocortical, cardiovascular, and emotional functioning in children

Brooks B Gump, Jacki Reihman, Paul Stewart, Ed Lonky, Tom Darvill, Douglas A. Granger, Karen A. Matthews

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Maternal depression has a number of adverse effects on children. In the present study, maternal depressive symptoms were assessed (using the Center for Epidemiological Studies Depression Scale) when their child was 3 months, 6 months, 1 year, 2 years, 4.25 years, 6 years, 7 years, 8 years, and 10 years of age. At 9.5 years of age, children's (94 females, 82 males) depressive symptoms as well as cardiovascular and cortisol levels during baseline and two psychologically stressful tasks were measured. Using multilevel modeling, maternal depressive symptom trajectories were considered in relation to their child's adrenocortical and cardiovascular responses to acute stress. Our goal was to determine maternal depressive symptom trajectories for children with elevated cardiovascular and cortisol reactivity to acute stress and elevated depressive symptoms. In general, those mothers with chronically elevated depressive symptoms over their child's life span had children with lower initial cortisol, higher cardiac output and stroke volume in response to acute stress, lower vascular resistance during acute stress tasks, and significantly more depressive symptoms at 9.5 years of age. These results are discussed in the context of established associations among hypothalamic-pituitary-adrenal axis dysregulation, depression, and cardiovascular disease.

Original languageEnglish (US)
Pages (from-to)207-225
Number of pages19
JournalDevelopment and Psychopathology
Volume21
Issue number1
DOIs
StatePublished - 2009
Externally publishedYes

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Mothers
Depression
Hydrocortisone
High Cardiac Output
Cardiac Volume
Vascular Resistance
Stroke Volume
Epidemiologic Studies
Cardiovascular Diseases

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

Cite this

Trajectories of maternal depressive symptoms over her child's life span : Relation to adrenocortical, cardiovascular, and emotional functioning in children. / Gump, Brooks B; Reihman, Jacki; Stewart, Paul; Lonky, Ed; Darvill, Tom; Granger, Douglas A.; Matthews, Karen A.

In: Development and Psychopathology, Vol. 21, No. 1, 2009, p. 207-225.

Research output: Contribution to journalArticle

Gump, Brooks B ; Reihman, Jacki ; Stewart, Paul ; Lonky, Ed ; Darvill, Tom ; Granger, Douglas A. ; Matthews, Karen A. / Trajectories of maternal depressive symptoms over her child's life span : Relation to adrenocortical, cardiovascular, and emotional functioning in children. In: Development and Psychopathology. 2009 ; Vol. 21, No. 1. pp. 207-225.
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