The rapidly evolving field of plant centromeres

Anne E. Hall; Kevin C. Keith; Sarah E. Hall; Gregory P. Copenhaver; Daphne Preuss

doi:10.1016/j.pbi.2004.01.008

The rapidly evolving field of plant centromeres

Anne E. Hall, Kevin C. Keith, Sarah E. Hall, Gregory P. Copenhaver, Daphne Preuss

Research output: Contribution to journal › Review article › peer-review

46 Scopus citations

Abstract

Meiotic and mitotic chromosome segregation are highly conserved in eukaryotic organisms, yet centromeres - the chromosomal sites that mediate segregation - evolve extremely rapidly. Plant centromeres have DNA elements that are shared across species, yet they diverge rapidly through large- and small-scale changes. Over evolutionary time-scales, centromeres migrate to non-centromeric regions and, in plants, heterochromatic knobs can acquire centromere activity. Discerning the functional significance of these changes will require comparative analyses of closely related species. Combined with functional assays, continued efforts in plant genomics will uncover key DNA elements that allow centromeres to retain their role in chromosome segregation while allowing rapid evolution.

Original language	English (US)
Pages (from-to)	108-114
Number of pages	7
Journal	Current Opinion in Plant Biology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/j.pbi.2004.01.008
State	Published - Apr 1 2004
Externally published	Yes

Keywords

BAC
Bacterial artificial chromosome
CEN4
CENP-A
CRM
CRR
Centromere protein-A
Centromere-specific retrotransposon of maize
Centromere-specific retrotransposon of rice
Centromere4
FISH
Fluorescent in situ hybridization

ASJC Scopus subject areas

Plant Science

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10.1016/j.pbi.2004.01.008

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title = "The rapidly evolving field of plant centromeres",

abstract = "Meiotic and mitotic chromosome segregation are highly conserved in eukaryotic organisms, yet centromeres - the chromosomal sites that mediate segregation - evolve extremely rapidly. Plant centromeres have DNA elements that are shared across species, yet they diverge rapidly through large- and small-scale changes. Over evolutionary time-scales, centromeres migrate to non-centromeric regions and, in plants, heterochromatic knobs can acquire centromere activity. Discerning the functional significance of these changes will require comparative analyses of closely related species. Combined with functional assays, continued efforts in plant genomics will uncover key DNA elements that allow centromeres to retain their role in chromosome segregation while allowing rapid evolution.",

keywords = "BAC, Bacterial artificial chromosome, CEN4, CENP-A, CRM, CRR, Centromere protein-A, Centromere-specific retrotransposon of maize, Centromere-specific retrotransposon of rice, Centromere4, FISH, Fluorescent in situ hybridization",

author = "Hall, {Anne E.} and Keith, {Kevin C.} and Hall, {Sarah E.} and Copenhaver, {Gregory P.} and Daphne Preuss",

year = "2004",

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language = "English (US)",

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journal = "Current Opinion in Plant Biology",

issn = "1369-5266",

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T1 - The rapidly evolving field of plant centromeres

AU - Hall, Anne E.

AU - Keith, Kevin C.

AU - Hall, Sarah E.

AU - Copenhaver, Gregory P.

AU - Preuss, Daphne

PY - 2004/4/1

Y1 - 2004/4/1

N2 - Meiotic and mitotic chromosome segregation are highly conserved in eukaryotic organisms, yet centromeres - the chromosomal sites that mediate segregation - evolve extremely rapidly. Plant centromeres have DNA elements that are shared across species, yet they diverge rapidly through large- and small-scale changes. Over evolutionary time-scales, centromeres migrate to non-centromeric regions and, in plants, heterochromatic knobs can acquire centromere activity. Discerning the functional significance of these changes will require comparative analyses of closely related species. Combined with functional assays, continued efforts in plant genomics will uncover key DNA elements that allow centromeres to retain their role in chromosome segregation while allowing rapid evolution.

AB - Meiotic and mitotic chromosome segregation are highly conserved in eukaryotic organisms, yet centromeres - the chromosomal sites that mediate segregation - evolve extremely rapidly. Plant centromeres have DNA elements that are shared across species, yet they diverge rapidly through large- and small-scale changes. Over evolutionary time-scales, centromeres migrate to non-centromeric regions and, in plants, heterochromatic knobs can acquire centromere activity. Discerning the functional significance of these changes will require comparative analyses of closely related species. Combined with functional assays, continued efforts in plant genomics will uncover key DNA elements that allow centromeres to retain their role in chromosome segregation while allowing rapid evolution.

KW - BAC

KW - Bacterial artificial chromosome

KW - CEN4

KW - CENP-A

KW - CRM

KW - CRR

KW - Centromere protein-A

KW - Centromere-specific retrotransposon of maize

KW - Centromere-specific retrotransposon of rice

KW - Centromere4

KW - FISH

KW - Fluorescent in situ hybridization

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DO - 10.1016/j.pbi.2004.01.008

M3 - Review article

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JO - Current Opinion in Plant Biology

JF - Current Opinion in Plant Biology

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