The Polygenic Risk Score of Subjective Well-Being, Self-Employment, and Earnings Among Older Individuals*

Pankaj C. Patel, Cornelius A. Rietveld, Marcus T. Wolfe, Johan Wiklund

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We investigate whether the polygenic risk score (PRS) of subjective well-being (SWB), a weighted combination of multiple genetic variants which captures an individual’s time-invariant genetic predisposition to SWB, influences the choice of self-employment and whether it explains differences in earnings between older self-employed and employed workers. In a sample of 4,571 individuals (50 to 65 years old) representing 14,937 individual-year observations from the Health and Retirement Study, we find that the PRS of SWB is positively associated with self-employment and earnings. However, contrary to our expectations, the positive association with earnings is not significantly different between self-employed and employed individuals.

Original languageEnglish (US)
Pages (from-to)440-466
Number of pages27
JournalEntrepreneurship: Theory and Practice
Volume45
Issue number2
DOIs
StatePublished - Mar 2021

Keywords

  • earnings
  • occupational choice
  • polygenic risk score
  • self-employment
  • subjective well-being

ASJC Scopus subject areas

  • Business and International Management
  • Economics and Econometrics

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