The dihydropyrone Diels-Alder reaction: Development and application to the synthesis of highly functionalized 1-oxa-4-decalones

Punit P. Seth, Deqi Chen, Junquan Wang, Xiuchun Gao, Nancy I. Totah

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

A facile method for the synthesis of highly functionalized 1-oxadecalone derivatives is described via the Diels-Alder reaction of 2,3-dihydro-4-pyrone dienophiles with electron rich dienes. By this process a variety of functional groups and substitution patterns can be incorporated into the oxadecalone framework. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)10185-10195
Number of pages11
JournalTetrahedron
Volume56
Issue number52
DOIs
StatePublished - Dec 22 2000
Externally publishedYes

Keywords

  • Cycloaddition
  • Diels-Alder reactions
  • Pyrone

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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