A facile method for the synthesis of highly functionalized 1-oxadecalone derivatives is described via the Diels-Alder reaction of 2,3-dihydro-4-pyrone dienophiles with electron rich dienes. By this process a variety of functional groups and substitution patterns can be incorporated into the oxadecalone framework. (C) 2000 Elsevier Science Ltd.
|Original language||English (US)|
|Number of pages||11|
|State||Published - Dec 22 2000|
- Diels-Alder reactions
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry