The correlation between 13C chemical shifts of DNA and interstrand purine-purine clash

You jie Zhang; Ke yu Wang; P. N. Borer; G. C. Levy

The correlation between ¹³C chemical shifts of DNA and interstrand purine-purine clash

You jie Zhang, Ke yu Wang, P. N. Borer, G. C. Levy

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The correlation between ¹³C chemical shifts of DNA and structure parameters (the main axis helix twist angle Ω, base-plane roll angle ρ{variant}, main chain torsion angle δ and propeller twist angle ω) has been discovered and proved indirectly. The carbons relating to the structure parameters have been found and interpreted theoretically. Relative variations in chemical shifts of these carbons obviously reflect purine-purine clash (steric hindrance) and have been compared with sum functions Σ of Calladine-Dickerson rules. It would be possible to provide the information about conformation of DNA from ¹³C NMR spectra and to observe the structure parameters of Ω, ρ{variant}, δ and ω of DNA in solution.

Original language	English (US)
Pages (from-to)	1416-1424
Number of pages	9
Journal	Science in China (Scientia Sinica) Series B
Volume	35
Issue number	12
State	Published - Dec 1 1992

Keywords

C NMR
Calladine-Dickerson rules
DNA
purine-purine clash

ASJC Scopus subject areas

Environmental Science(all)
Engineering(all)
Earth and Planetary Sciences(all)

Access to Document

Fingerprint Dive into the research topics of 'The correlation between <sup>13</sup>C chemical shifts of DNA and interstrand purine-purine clash'. Together they form a unique fingerprint.

Cite this

@article{f45066616d124799853118c01a6cd431,

title = "The correlation between 13C chemical shifts of DNA and interstrand purine-purine clash",

abstract = "The correlation between 13C chemical shifts of DNA and structure parameters (the main axis helix twist angle Ω, base-plane roll angle ρ{variant}, main chain torsion angle δ and propeller twist angle ω) has been discovered and proved indirectly. The carbons relating to the structure parameters have been found and interpreted theoretically. Relative variations in chemical shifts of these carbons obviously reflect purine-purine clash (steric hindrance) and have been compared with sum functions Σ of Calladine-Dickerson rules. It would be possible to provide the information about conformation of DNA from 13C NMR spectra and to observe the structure parameters of Ω, ρ{variant}, δ and ω of DNA in solution.",

keywords = "C NMR, Calladine-Dickerson rules, DNA, purine-purine clash",

author = "Zhang, {You jie} and Wang, {Ke yu} and Borer, {P. N.} and Levy, {G. C.}",

year = "1992",

month = dec,

day = "1",

language = "English (US)",

volume = "35",

pages = "1416--1424",

journal = "Science in China. Series B, Chemistry, life sciences & earth sciences",

issn = "1001-652X",

publisher = "Science in China Press",

number = "12",

}

TY - JOUR

T1 - The correlation between 13C chemical shifts of DNA and interstrand purine-purine clash

AU - Zhang, You jie

AU - Wang, Ke yu

AU - Borer, P. N.

AU - Levy, G. C.

PY - 1992/12/1

Y1 - 1992/12/1

N2 - The correlation between 13C chemical shifts of DNA and structure parameters (the main axis helix twist angle Ω, base-plane roll angle ρ{variant}, main chain torsion angle δ and propeller twist angle ω) has been discovered and proved indirectly. The carbons relating to the structure parameters have been found and interpreted theoretically. Relative variations in chemical shifts of these carbons obviously reflect purine-purine clash (steric hindrance) and have been compared with sum functions Σ of Calladine-Dickerson rules. It would be possible to provide the information about conformation of DNA from 13C NMR spectra and to observe the structure parameters of Ω, ρ{variant}, δ and ω of DNA in solution.

AB - The correlation between 13C chemical shifts of DNA and structure parameters (the main axis helix twist angle Ω, base-plane roll angle ρ{variant}, main chain torsion angle δ and propeller twist angle ω) has been discovered and proved indirectly. The carbons relating to the structure parameters have been found and interpreted theoretically. Relative variations in chemical shifts of these carbons obviously reflect purine-purine clash (steric hindrance) and have been compared with sum functions Σ of Calladine-Dickerson rules. It would be possible to provide the information about conformation of DNA from 13C NMR spectra and to observe the structure parameters of Ω, ρ{variant}, δ and ω of DNA in solution.

KW - C NMR

KW - Calladine-Dickerson rules

KW - DNA

KW - purine-purine clash

UR - http://www.scopus.com/inward/record.url?scp=0011388101&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0011388101&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0011388101

VL - 35

SP - 1416

EP - 1424

JO - Science in China. Series B, Chemistry, life sciences & earth sciences

JF - Science in China. Series B, Chemistry, life sciences & earth sciences

SN - 1001-652X

IS - 12

ER -