TY - JOUR
T1 - The brain in flux
T2 - Genetic, physiologic, and therapeutic perspectives on transporters in the CNS
AU - Hewett, Sandra J.
AU - Prado, Vania F.
AU - Robinson, Michael B.
N1 - Funding Information:
The organizing committee selected trainees to receive awards that helped partially defray travel and meeting expenses. The US-based student travel awards were supported by an NIH R13 grant (R13 NS113618), while the international students’ awards were supported by conference funds. Pre-doctoral winners were Jenny Aguilar, Sebastain Almendras, Martin Bach, Kelsey Benton, Shane Berger, Gabriella DiCarlo, Melinda Hershey, Lisa Konrad, Marco Niello, Onyedikachi Ojiakor, Mariana Olivera, Heather Sosnoski, and Alyssa West. Post-doctoral winners were Lorena Areal, Carmen Herenbrink, Zila Martinez-Lozada, Laura McNair, Asit Rai and Diana Sakae. The organizing committee also selected one junior faculty for a travel award that provided partial support for attendance to the meeting. The winner was Heinrich Matthies.
Funding Information:
The organizers of this meeting are grateful to those who provided support that enabled the 4th biennial meeting, titled ?The Brain in Flux: Genetic, Physiologic, and Therapeutic Perspectives on Transporters in the CNS?, including the National Institites of Neurologic Disease and Stroke (R13 NS113618), the International Society for Neurochemistry, Neurochemistry International (Elsevier), and Labex BioPsy.
Publisher Copyright:
© 2021
PY - 2021/3
Y1 - 2021/3
N2 - Active and passive transporters constitute a gene family of approximately 2000 members. These proteins are required for import and export across the blood brain barrier, clearance of neurotransmitters, inter-cellular solute transfer, and transport across the membranes of subcellular organelles. Neurologic, neurodevelopmental, and psychiatric diseases have been linked to alterations in function and/or mutations in every one of these types of transporters, and many of the transporters are targeted by therapeutics. This is the 4th biennial special edition of Neurochemistry International that originates from a scientific meeting devoted to studies of transporters and their relationship to brain function and to neurodevelopmental, neurologic, and psychiatric disorders. This meeting provides the only international forum for the presentation and discussion of cutting-edge research on brain transporters covering fundamental aspects of transporter structure, function, and trafficking. Scientists describe the novel approaches being used to link this information to physiology/circuit function and behavior. The meeting also addresses translational topics surrounding mouse models of brain transporter disorders, novel human brain disorders arising from transporter mutations, and innovative therapeutic approaches centered on modification of transporter function. This special issue includes a sampling of review articles that address timely questions of the field and several primary research articles.
AB - Active and passive transporters constitute a gene family of approximately 2000 members. These proteins are required for import and export across the blood brain barrier, clearance of neurotransmitters, inter-cellular solute transfer, and transport across the membranes of subcellular organelles. Neurologic, neurodevelopmental, and psychiatric diseases have been linked to alterations in function and/or mutations in every one of these types of transporters, and many of the transporters are targeted by therapeutics. This is the 4th biennial special edition of Neurochemistry International that originates from a scientific meeting devoted to studies of transporters and their relationship to brain function and to neurodevelopmental, neurologic, and psychiatric disorders. This meeting provides the only international forum for the presentation and discussion of cutting-edge research on brain transporters covering fundamental aspects of transporter structure, function, and trafficking. Scientists describe the novel approaches being used to link this information to physiology/circuit function and behavior. The meeting also addresses translational topics surrounding mouse models of brain transporter disorders, novel human brain disorders arising from transporter mutations, and innovative therapeutic approaches centered on modification of transporter function. This special issue includes a sampling of review articles that address timely questions of the field and several primary research articles.
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U2 - 10.1016/j.neuint.2021.104980
DO - 10.1016/j.neuint.2021.104980
M3 - Editorial
C2 - 33524471
AN - SCOPUS:85100418286
SN - 0197-0186
VL - 144
JO - Neurochemistry International
JF - Neurochemistry International
M1 - 104980
ER -