L. L. Tavlarides, W. R. Haas

Research output: Contribution to conferencePaper


Operation of enzyme reactors may be improved by use of the proper temperature operating policy. For the endothermic reversible isomerization of D-glucose to D-fructose, via glucose isomerase, optimal policy suggests operation at as high a temperature as possible to enhance both equilibrium conversion and rate of reaction. Conversely, when the temperature exceeds a certain level, enzyme denaturation and consequently a diminished rate of reaction occurs. The optimal temperature policy for the above reaction system in a batch or plug flow reactor can be formulated using the calculus of variations. The results indicate that under similar conditions 10% less deactivation occurs by the proposed temperature control method than by use of the optimum isothermal temperature. Mathematical equations derived for designing purposes are included in this brief report.

Original languageEnglish (US)
Number of pages4
StatePublished - Jan 1 1974
Externally publishedYes
EventEng Found Conf on Enzyme Eng, 2nd, Proc - Henniker, NH, USA
Duration: Aug 5 1973Aug 10 1973


OtherEng Found Conf on Enzyme Eng, 2nd, Proc
CityHenniker, NH, USA

ASJC Scopus subject areas

  • Engineering(all)

Fingerprint Dive into the research topics of 'TERMPERATURE EFFECTS ON THE DESIGN OF ENZYME REACTORS.'. Together they form a unique fingerprint.

  • Cite this

    Tavlarides, L. L., & Haas, W. R. (1974). TERMPERATURE EFFECTS ON THE DESIGN OF ENZYME REACTORS.. 279-282. Paper presented at Eng Found Conf on Enzyme Eng, 2nd, Proc, Henniker, NH, USA, .