Tandem elimination-oxidation of tertiary benzylic alcohols with an oxoammonium salt

Rowan I.L. Meador, Robert E. Anderson, John D. Chisholm

Research output: Contribution to journalArticlepeer-review

Abstract

Tertiary benzylic alcohols react with oxoammonium salts, undergoing a tandem elimination/allylic oxidation to provide an allylic ether product in a single step. This mode of reactivity provides a rapid entry into allylic ethers from certain benzylic tertiary alcohols. The allylic ether may be cleaved under reductive conditions to reveal the allylic alcohol.

Original languageEnglish (US)
Pages (from-to)6233-6236
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume19
Issue number28
DOIs
StatePublished - Jul 28 2021

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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