Tailoring quantum dot interfaces for improved biofunctionality and energy transfer

Joshua Zylstra, Rabeka Alam, Hyunjoo Han, Robert Patrick Doyle, Mathew M Maye

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Over the past decade quantum dots (qdots) have emerged as a premier biological labeling tool due to their unique photophysical properties. In order to take advantage of these properties, a lot of surface chemistry design work needs to take place due to the need of phase transfer to aqueous buffers, as well as the need to preserve both photophysical and colloidal stability. This chapter first briefly reviews a number of functionalization strategies available to researchers, and then focuses on our groups strategy. In particular, the use the amino acid L-histidine to facilitate both phase trasfer, ligand exchange, as well as direct biological functionalization. The binding mechanism and properties of the histidine-capping at the qdots is reviewed, as well as the use of resonance energy transfer (FRET and BRET) to probe the abiotic-biotic interface.

Original languageEnglish (US)
Title of host publicationACS Symposium Series
PublisherAmerican Chemical Society
Pages59-79
Number of pages21
Volume1112
ISBN (Print)9780841227750
DOIs
StatePublished - Nov 26 2012

Publication series

NameACS Symposium Series
Volume1112
ISSN (Print)00976156
ISSN (Electronic)19475918

Fingerprint

Histidine
Energy transfer
Semiconductor quantum dots
Surface chemistry
Labeling
Amino acids
Buffers
Ligands
Amino Acids

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Zylstra, J., Alam, R., Han, H., Doyle, R. P., & Maye, M. M. (2012). Tailoring quantum dot interfaces for improved biofunctionality and energy transfer. In ACS Symposium Series (Vol. 1112, pp. 59-79). (ACS Symposium Series; Vol. 1112). American Chemical Society. https://doi.org/10.1021/bk-2012-1112.ch003

Tailoring quantum dot interfaces for improved biofunctionality and energy transfer. / Zylstra, Joshua; Alam, Rabeka; Han, Hyunjoo; Doyle, Robert Patrick; Maye, Mathew M.

ACS Symposium Series. Vol. 1112 American Chemical Society, 2012. p. 59-79 (ACS Symposium Series; Vol. 1112).

Research output: Chapter in Book/Report/Conference proceedingChapter

Zylstra, J, Alam, R, Han, H, Doyle, RP & Maye, MM 2012, Tailoring quantum dot interfaces for improved biofunctionality and energy transfer. in ACS Symposium Series. vol. 1112, ACS Symposium Series, vol. 1112, American Chemical Society, pp. 59-79. https://doi.org/10.1021/bk-2012-1112.ch003
Zylstra J, Alam R, Han H, Doyle RP, Maye MM. Tailoring quantum dot interfaces for improved biofunctionality and energy transfer. In ACS Symposium Series. Vol. 1112. American Chemical Society. 2012. p. 59-79. (ACS Symposium Series). https://doi.org/10.1021/bk-2012-1112.ch003
Zylstra, Joshua ; Alam, Rabeka ; Han, Hyunjoo ; Doyle, Robert Patrick ; Maye, Mathew M. / Tailoring quantum dot interfaces for improved biofunctionality and energy transfer. ACS Symposium Series. Vol. 1112 American Chemical Society, 2012. pp. 59-79 (ACS Symposium Series).
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