Synthetic disugar hydrocarbons as signaling analog for microbial control

Guirong Wang (Inventor), Yan-Yeung Luk (Inventor)

Research output: Patent

Abstract

Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.
Original languageEnglish (US)
StatePublished - Sep 19 2019

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