Synthetic Disugar Hydrocarbons as Natural Analogs to Control Microbial Behaviors

Guirong Wang (Inventor), Yan-Yeung Luk (Inventor)

Research output: ResearchPatent

Abstract

Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.
LanguageEnglish (US)
StatePublished - Jan 19 2017

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disaccharide
natural analog
hydrocarbon
swarming
pneumonia
motility
adhesion
biofilm
bacterium
experiment
library

Cite this

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