Synthetic Disugar Hydrocarbons as Natural Analogs to Control Microbial Behaviors

Guirong Wang; Yan-Yeung Luk

Synthetic Disugar Hydrocarbons as Natural Analogs to Control Microbial Behaviors

Guirong Wang (Inventor), Yan-Yeung Luk (Inventor)

Research output: Patent

Abstract

Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.

Original language	English (US)
Patent number	11,357,786
Priority date	4/3/14
Filing date	10/2/20
State	Published - Jan 28 2021

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title = "Synthetic Disugar Hydrocarbons as Natural Analogs to Control Microbial Behaviors",

abstract = "Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.",

author = "Guirong Wang and Yan-Yeung Luk",

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language = "English (US)",

type = "Patent",

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AU - Wang, Guirong

AU - Luk, Yan-Yeung

PY - 2021/1/28

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N2 - Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.

AB - Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs were tested in several experiment for the impact on various Pseudomonas aeruginosa populations and compared against existing compounds to determine efficacy and utility. Certain DSHs were also to determine the ability to clear bacteria in a mouse pneumonia model.

M3 - Patent

M1 - 11,357,786

Y2 - 2020/10/02

ER -

Synthetic Disugar Hydrocarbons as Natural Analogs to Control Microbial Behaviors

Abstract

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