Synthesis of (2S,3S,8S,9S)-Adda from D-glucose

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23 Scopus citations

Abstract

The N-trifluoroacetyl derivative of the novel β-amino acid (2S,3S,8S,9S)-Adda methyl ester 4 has been prepared from the D-glucose derived oxazoline 7. A key step in the construction of 4 was the generation of the E,E decadienoate system via dissolving metal reduction of vicinal bis-mesylate 15.

Original languageEnglish (US)
Pages (from-to)5645-5648
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number32
DOIs
StatePublished - Aug 5 1996

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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