Super-compressible DNA nanoparticle lattices

Sunita Srivastava, Dmytro Nykypanchuk, Mathew M Maye, Alexei V. Tkachenko, Oleg Gang

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The compression properties of DNA-nanoparticle assemblies were studied by measuring their response to the applied osmotic pressure. The lattices of nanoparticles interconnected with DNA exhibit an isotropic transformation under compression with a remarkably strong decrease of the lattice constant, up to a factor of about 1.8, corresponding to more than 80% of the volume reduction. Using insitu small angle X-ray scattering and optical microscopy, we probe the DNA-induced effective interparticle interactions by measuring the macroscopic and nanoscale compression behaviours as a function of the applied osmotic stress. The force field extracted from experimental data can be well described by a theoretical model that takes into account confinement of DNA chains in the interstitial regions. We show that compression properties of these systems can be tuned via DNA molecular design.

Original languageEnglish (US)
Pages (from-to)10452-10457
Number of pages6
JournalSoft Matter
Volume9
Issue number44
DOIs
StatePublished - Nov 28 2013

Fingerprint

deoxyribonucleic acid
Nanoparticles
nanoparticles
DNA
DNA Probes
X ray scattering
osmosis
Lattice constants
Optical microscopy
assemblies
field theory (physics)
interstitials
microscopy
probes
scattering
x rays
interactions

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

Cite this

Srivastava, S., Nykypanchuk, D., Maye, M. M., Tkachenko, A. V., & Gang, O. (2013). Super-compressible DNA nanoparticle lattices. Soft Matter, 9(44), 10452-10457. https://doi.org/10.1039/c3sm51289d

Super-compressible DNA nanoparticle lattices. / Srivastava, Sunita; Nykypanchuk, Dmytro; Maye, Mathew M; Tkachenko, Alexei V.; Gang, Oleg.

In: Soft Matter, Vol. 9, No. 44, 28.11.2013, p. 10452-10457.

Research output: Contribution to journalArticle

Srivastava, S, Nykypanchuk, D, Maye, MM, Tkachenko, AV & Gang, O 2013, 'Super-compressible DNA nanoparticle lattices', Soft Matter, vol. 9, no. 44, pp. 10452-10457. https://doi.org/10.1039/c3sm51289d
Srivastava S, Nykypanchuk D, Maye MM, Tkachenko AV, Gang O. Super-compressible DNA nanoparticle lattices. Soft Matter. 2013 Nov 28;9(44):10452-10457. https://doi.org/10.1039/c3sm51289d
Srivastava, Sunita ; Nykypanchuk, Dmytro ; Maye, Mathew M ; Tkachenko, Alexei V. ; Gang, Oleg. / Super-compressible DNA nanoparticle lattices. In: Soft Matter. 2013 ; Vol. 9, No. 44. pp. 10452-10457.
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