Site directed maleimide bifunctional chelators for the M(CO) 3+ core (M = 99mTc, Re)

Sangeeta Ray Banerjee, John W. Babich, Jon Zubieta

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

A series of bifunctional chelates containing a tridentate donor set for complexation of the M(CO)3+ core and a maleimide group for site-specific coupling to peptides and proteins containing free thiol groups has been prepared and their Re(CO)3+ complexes and glutathione conjugates structurally characterized. The flexibility of design allows preparation of ligands suitable for both fluorescence imaging, radioimaging and radiotherapeutic studies of proteins and peptides as well as other biopolymers using site specific conjugation.

Original languageEnglish (US)
Pages (from-to)1784-1786
Number of pages3
JournalChemical Communications
Issue number13
DOIs
StatePublished - Apr 7 2005

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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