Sensing the unreachable: challenges and opportunities in biofilm detection

Yikang Xu, Yousr Dhaouadi, Paul Stoodley, Dacheng Ren

Research output: Contribution to journalReview articlepeer-review

60 Scopus citations


Bacteria can attach to essentially all materials and form multicellular biofilms with high-level tolerance to antimicrobials. Detrimental biofilms are responsible for a variety of problems ranging from food and water contamination, bio-corrosion, to drug resistant infections. Besides the challenges in control, biofilms are also difficult to detect due to the lack of biofilm-specific biomarkers and methods for non-destructive imaging. In this article, we present a concise review of recent advancements in this field, with a focus on medical device-associated infections. We also discuss the technologies that have potential for non-destructive detection of bacterial biofilms.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalCurrent Opinion in Biotechnology
StatePublished - Aug 2020

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering


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