Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation

Guannan Liu, Adam Patch, Fatmagül Bahar, David Yllanes, Roy Welch, M Cristina Marchetti, Shashi Thutupalli, Joshua W. Shaevitz

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Combining high-resolution single cell tracking experiments with numerical simulations, we show that starvation-induced fruiting body formation in Myxococcus xanthus is a phase separation driven by cells that tune their motility over time. The phase separation can be understood in terms of cell density and a dimensionless Péclet number that captures cell motility through speed and reversal frequency. Our work suggests that M. xanthus takes advantage of a self-driven nonequilibrium phase transition that can be controlled at the single cell level.

Original languageEnglish (US)
Article number248102
JournalPhysical Review Letters
Volume122
Issue number24
DOIs
StatePublished - Jun 20 2019

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cells
locomotion
dimensionless numbers
high resolution
simulation

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Liu, G., Patch, A., Bahar, F., Yllanes, D., Welch, R., Marchetti, M. C., ... Shaevitz, J. W. (2019). Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation. Physical Review Letters, 122(24), [248102]. https://doi.org/10.1103/PhysRevLett.122.248102

Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation. / Liu, Guannan; Patch, Adam; Bahar, Fatmagül; Yllanes, David; Welch, Roy; Marchetti, M Cristina; Thutupalli, Shashi; Shaevitz, Joshua W.

In: Physical Review Letters, Vol. 122, No. 24, 248102, 20.06.2019.

Research output: Contribution to journalArticle

Liu, G, Patch, A, Bahar, F, Yllanes, D, Welch, R, Marchetti, MC, Thutupalli, S & Shaevitz, JW 2019, 'Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation', Physical Review Letters, vol. 122, no. 24, 248102. https://doi.org/10.1103/PhysRevLett.122.248102
Liu, Guannan ; Patch, Adam ; Bahar, Fatmagül ; Yllanes, David ; Welch, Roy ; Marchetti, M Cristina ; Thutupalli, Shashi ; Shaevitz, Joshua W. / Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation. In: Physical Review Letters. 2019 ; Vol. 122, No. 24.
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