Saposin B Binds the Lipofuscin Bisretinoid A2E and Prevents its Enzymatic and Photo Degradation

Robert Patrick Doyle (Inventor), Kelsey J. Moody (Inventor)

Research output: Patent

Abstract

Disclosed herein are methods and compositions useful in the treatment and/or prevention of a disease or indication associated with accumulation of a bisretinoid, for example A2E. In many embodiments, the disclosed methods and compositions are useful in treating an eye disease, for example macular degeneration.
Original languageEnglish (US)
Patent number10,813,981
Priority date2/3/17
Filing date2/1/18
StateAccepted/In press - Oct 17 2020

Fingerprint

Dive into the research topics of 'Saposin B Binds the Lipofuscin Bisretinoid A2E and Prevents its Enzymatic and Photo Degradation'. Together they form a unique fingerprint.

Cite this