Ruthenium Hydride Catalyzed Silylvinylation of Internal Alkynes Using Ethylene as an Additive

Robert J. Wilson, Lauren Kaminsky, Ijaz Ahmed, Daniel A. Clark

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

An efficient synthetic strategy for the regiospecific silylvinylation of internal alkynes is described. This transformation is catalyzed by RuHCl(CO)(SIMes)PPh3 and provides a net 5-exo-dig trans-silylvinylation of internal alkynes. Ethylene was used to decrease reaction times and displayed altered selectivity at increased pressure. Furthermore, alkyl-substituted alkynes were acceptable substrates at 80 psi of ethylene.

Original languageEnglish (US)
Pages (from-to)8290-8299
Number of pages10
JournalJournal of Organic Chemistry
Volume80
Issue number16
DOIs
StatePublished - Aug 21 2015

ASJC Scopus subject areas

  • Organic Chemistry

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