The cycloisomerization of vinyl silicon-tethered 1,7-enynes has been accomplished using catalytic Cp∗Ru(COD)Cl. The products possess a new silane moiety and trisubstituted alkenes as part of the diene system. The reaction scope includes aryl, alkyl, vinyl, and cyclopropyl alkyne functionalities. Silicon was found not to be a mandatory component of the tether. The utility of the products was demonstrated through manipulation of the vinyl silane and Diels-Alder chemistry. (Chemical Equation Presented).
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry