Retrograde amnesia produced by subseizure amygdala stimulation

Paul E. Gold, John Macri, James L. McGaugh

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Rats received low-level bilateral electrical stimulation of the amygdala after training on a one-trial inhibitory (passive) avoidance task. The stimulation did not produce brain seizures. Animals which received the stimulation 5 sec or 1 hr, but not 6 hr, after training had retrograde amnesia as measured on a retention test 24 hr later. The amnesia was permanent over an 8 day period. Following extinction and retraining, amygdala stimulation produced retrograde amnesia only in animals which had complete amnesia (i.e., animals which performed at the naive level) for the first training experience.

Original languageEnglish (US)
Pages (from-to)671-680
Number of pages10
JournalBehavioral Biology
Volume9
Issue number6
DOIs
StatePublished - Dec 1973
Externally publishedYes

ASJC Scopus subject areas

  • General Environmental Science
  • General Earth and Planetary Sciences

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