Retrograde amnesia after localized brain shock in passive-avoidance learning

Paul Ernest Gold, William Farrell, Richard A. King

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Rats were trained on a one-trial passive-avoidance task. Post-trial brain shock was administered through skull screws. This stimulation was given through either anterior or posterior skull placements at several current intensities. At two intensities anterior stimulation was found to produce significantly more retrograde amnesia than the corresponding posterior stimulation. The results are discussed in terms of (a) possible lower generalized brain seizure thresholds for anterior shocks, and (b) possible post-trial disruption of activity in the specific anterior brain structures importantly involved in memory for passive-avoidance learning.

Original languageEnglish (US)
Pages (from-to)709-712
Number of pages4
JournalPhysiology and Behavior
Volume7
Issue number5
DOIs
StatePublished - 1971
Externally publishedYes

Fingerprint

Retrograde Amnesia
Avoidance Learning
Shock
Skull
Brain
Seizures

Keywords

  • ECS
  • Electroconvulsive shock
  • Localization of ECS effects
  • Memory
  • Passive-avoidance learning
  • Retrograde amnesia

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Retrograde amnesia after localized brain shock in passive-avoidance learning. / Gold, Paul Ernest; Farrell, William; King, Richard A.

In: Physiology and Behavior, Vol. 7, No. 5, 1971, p. 709-712.

Research output: Contribution to journalArticle

Gold, Paul Ernest ; Farrell, William ; King, Richard A. / Retrograde amnesia after localized brain shock in passive-avoidance learning. In: Physiology and Behavior. 1971 ; Vol. 7, No. 5. pp. 709-712.
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