Relationship between amnesia and brain seizures in rats

Paul E. Gold, James L. McGaugh

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The brain stimulation intensity necessary to produce seizures and retrograde amnesia was examined at three locations: frontal cortex, posterior cortex, and a far posterior placement. Posterior cortex had the lowest brain seizure and retrograde amnesia thresholds; the far posterior placement had the highest brain seizure and retrograde amnesia thresholds. These results suggest that the amnesic properties of the brain stimulation may be linked in some way to brain seizures. However, the relationship is not a simple one; cortically elicited brain seizures are not always effective in disrupting memory.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalPhysiology and Behavior
Volume10
Issue number1
DOIs
StatePublished - Jan 1973
Externally publishedYes

Keywords

  • Brain seizures
  • Cortical stimulation
  • Electroconvulsive shock
  • Memory consolidation
  • Memory disruption
  • Retrograde amnesia

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Relationship between amnesia and brain seizures in rats'. Together they form a unique fingerprint.

Cite this