This work explores how data-locality in a web datacenter can impact the performance of the Memcache caching system. Memcache is a distributed key/value datastore used to cache frequently accessed data such as database requests, HTML page snippets, or any text string. Any client can store, manipulate, or retrieve data quickly by locating the data in the Memcache system using a hashing strategy based on the key. To speed Memcache, we explore alternate storage strategies where data is stored closer to the writer. Two novel Memcache architectures are proposed, based on multi-cpu caching strategies. A model is developed to predict Memcache performance given a web application's usage profile, network variables, and a memcache architecture. Five architecture variants are analyzed and further evaluated in a miniature web farm using the MediaWiki open-source web application. Our results verified our model and we observed a 66% reduction in core network traffic and a 23% reduction in Memcache response time under certain network conditions.