Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography

A. Ping Zhang; Xin Qu; Pranav Soman; Kolin C. Hribar; Jin W. Lee; Shaochen Chen; Sailing He

doi:10.1002/adma.201202024

Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography

A. Ping Zhang, Xin Qu, Pranav Soman, Kolin C. Hribar, Jin W. Lee, Shaochen Chen, Sailing He

Research output: Contribution to journal › Article › peer-review

316 Scopus citations

Abstract

The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.

Original language	English (US)
Pages (from-to)	4266-4270
Number of pages	5
Journal	Advanced Materials
Volume	24
Issue number	31
DOIs	https://doi.org/10.1002/adma.201202024
State	Published - Aug 16 2012
Externally published	Yes

Keywords

cell culture
extracelluar microenviroment
maskless lithography
optical projection stereolithography
soft material

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201202024

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abstract = "The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.",

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AU - Zhang, A. Ping

AU - Qu, Xin

AU - Soman, Pranav

AU - Hribar, Kolin C.

AU - Lee, Jin W.

AU - Chen, Shaochen

AU - He, Sailing

PY - 2012/8/16

Y1 - 2012/8/16

N2 - The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.

AB - The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.

KW - cell culture

KW - extracelluar microenviroment

KW - maskless lithography

KW - optical projection stereolithography

KW - soft material

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JO - Advanced Materials

JF - Advanced Materials

IS - 31

ER -

Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography

Abstract

Keywords

ASJC Scopus subject areas

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