Psychological burden and caregiver-reported non-adherence to psychotropic medications among patients with schizophrenia

Irene A. Kretchy, Joseph Osafo, Samuel Agyei Agyemang, Bernard Appiah, Justice Nonvignon

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The study examined the association between psychological distress, caregiving burden and caregiver-reported medication adherence in 444 informal family caregivers of patients with schizophrenia. Participants were assessed on the Depression, Anxiety Stress Scale, Zarit Burden Interview and the Medication Adherence Report Scale. Caregivers reported a non-adherence rate of 54.5% among patients with schizophrenia. Poor adherence to antipsychotics was significantly associated with caregiver burden (p < 0.01) and experience of anxiety (p < 0.0001). The burden of caregiving should be considered during the assessment of adherence. The findings suggest a need for culturally appropriate interventions that improve antipsychotic adherence of outpatients with schizophrenia with specific attention to the burden of the caregiver.

Original languageEnglish (US)
Pages (from-to)289-294
Number of pages6
JournalPsychiatry Research
Volume259
DOIs
StatePublished - Jan 2018
Externally publishedYes

Keywords

  • Anxiety
  • Burden
  • Caregivers
  • Depression
  • Non-adherence
  • Psychotropic medications
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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