A process for forming protoanemonin from an amount of levulinic acid or an amount of α-Angelica lactone using oxidative dehydrogenation. Biomass-derived levulinic acid (LA) is a green platform chemical and, using an oxidative scission pathway can be transformed into cyclic intermediates, namely angelicalactones to form protoanemonin. The oxidative dehydrogenation may be heterogeneously catalyzed in a gas-phase to perform aerobic oxidation using a solid oxide such as vanadium oxide. Protoanemonin is an intriguing polyfunctional molecule that is uniquely suited to bio-based production, and can be synthesized in yields from 50%-75% during periods of transient reactor operation.
|Original language||English (US)|
|State||Published - Jul 15 2021|