Polarity sets the stage for cytokinesis

Heidi Hehnly, Stephen Doxsey

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Cell polarity is important for a number of processes, from chemotaxis to embryogenesis. Recent studies suggest a new role for polarity in the orchestration of events during the final cell separation step of cell division called abscission. Abscission shares several features with cell polarization, including rearrangement of phosphatidylinositols, reorganization of microtubules, and trafficking of exocyst-associated membranes. Here we focus on how the canonical pathways for cell polarization and cell migration may play a role in spatiotemporal membrane trafficking events required for the final stages of cytokinesis.

Original languageEnglish (US)
Pages (from-to)7-11
Number of pages5
JournalMolecular biology of the cell
Volume23
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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