Abstract
During embryonic cell divisions, cell size changes rapidly. Rathbun et al. identify in zebrafish embryos that mitotic centrosomes scale with changes in cell size. In addition, an embryonic cell spindle has asymmetric in size mitotic centrosomes, where the largest mitotic centrosome is placed toward the embryo center in a PLK1/4-dependent manner.
Original language | English (US) |
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Pages (from-to) | 4519-4527.e3 |
Journal | Current Biology |
Volume | 30 |
Issue number | 22 |
DOIs | |
State | Published - Nov 16 2020 |
Keywords
- C. elegans
- PCM
- PLK1
- PLK4
- centrosome
- embryo
- microtubules
- mitosis
- spindle
- zebrafish
ASJC Scopus subject areas
- General Neuroscience
- General Biochemistry, Genetics and Molecular Biology
- General Agricultural and Biological Sciences