TY - JOUR
T1 - Pattern formation and traveling waves in myxobacteria
T2 - Theory and modeling
AU - Igoshin, Oleg A.
AU - Mogilner, Alex
AU - Welch, Roy D.
AU - Kaiser, Dale
AU - Oster, George
PY - 2001/12/18
Y1 - 2001/12/18
N2 - Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, and cell motility can coordinate to produce collective behavior. This pattern of waves is qualitatively different from that observed in other social organisms, especially Dictyostelium discoideum, which depend on diffusible morphogens.
AB - Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, and cell motility can coordinate to produce collective behavior. This pattern of waves is qualitatively different from that observed in other social organisms, especially Dictyostelium discoideum, which depend on diffusible morphogens.
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U2 - 10.1073/pnas.221579598
DO - 10.1073/pnas.221579598
M3 - Article
C2 - 11752439
AN - SCOPUS:0035909945
VL - 98
SP - 14913
EP - 14918
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
SN - 0027-8424
IS - 26
ER -