Pattern formation and traveling waves in myxobacteria: Theory and modeling

Oleg A. Igoshin; Alex Mogilner; Roy D. Welch; Dale Kaiser; George Oster

doi:10.1073/pnas.221579598

Pattern formation and traveling waves in myxobacteria: Theory and modeling

Oleg A. Igoshin, Alex Mogilner, Roy D. Welch, Dale Kaiser, George Oster

Research output: Contribution to journal › Article

90 Scopus citations

Abstract

Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, and cell motility can coordinate to produce collective behavior. This pattern of waves is qualitatively different from that observed in other social organisms, especially Dictyostelium discoideum, which depend on diffusible morphogens.

Original language	English (US)
Pages (from-to)	14913-14918
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	98
Issue number	26
DOIs	https://doi.org/10.1073/pnas.221579598
State	Published - Dec 18 2001
Externally published	Yes

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Igoshin, O. A., Mogilner, A., Welch, R. D., Kaiser, D., & Oster, G. (2001). Pattern formation and traveling waves in myxobacteria: Theory and modeling. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 14913-14918. https://doi.org/10.1073/pnas.221579598

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