Painting proteins blue: β-(1-azulenyl)-l-alanine as a probe for studying protein-protein interactions

Yurii S. Moroz, Wolfgang Binder, Patrik Nygren, Gregory A. Caputo, Ivan V. Korendovych

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

We demonstrated that β-(1-azulenyl)-l-alanine, a fluorescent pseudoisosteric analog of tryptophan, exhibits weak environmental dependence and thus allows for using weak intrinsic quenchers, such as methionines, to monitor protein-protein interactions while not perturbing them.

Original languageEnglish (US)
Pages (from-to)490-492
Number of pages3
JournalChemical Communications
Volume49
Issue number5
DOIs
StatePublished - 2013

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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