Organoid intelligence: Integration of organoid technology and artificial intelligence in the new era of in vitro models

Huaiyu Shi, Andrew Kowalczewski, Danny Vu, Xiyuan Liu, Asif Salekin, Huaxiao Yang, Zhen Ma

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Organoid Intelligence ushers in a new era by seamlessly integrating cutting-edge organoid technology with the power of artificial intelligence. Organoids, three-dimensional miniature organ-like structures cultivated from stem cells, offer an unparalleled opportunity to simulate complex human organ systems in vitro. Through the convergence of organoid technology and AI, researchers gain the means to accelerate discoveries and insights across various disciplines. Artificial intelligence algorithms enable the comprehensive analysis of intricate organoid behaviors, intricate cellular interactions, and dynamic responses to stimuli. This synergy empowers the development of predictive models, precise disease simulations, and personalized medicine approaches, revolutionizing our understanding of human development, disease mechanisms, and therapeutic interventions. Organoid Intelligence holds the promise of reshaping how we perceive in vitro modeling, propelling us toward a future where these advanced systems play a pivotal role in biomedical research and drug development.

Original languageEnglish (US)
Article number100276
JournalMedicine in Novel Technology and Devices
Volume21
DOIs
StatePublished - Mar 2024

Keywords

  • Artificial intelligence
  • Deep learning
  • Machine learning
  • Organoids
  • Stem cells

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Computer Science Applications

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