Organizing Knowledge in Knowledgebases: A Case Study

This paper uses the knowledgebases in the biomedical field as a case study to discuss the characteristics and requirements of knowledge organization (KO) practices and products by looking at the constructs, cross-linking, and curation methods. Modern knowledgebases such as Gene Ontology and Disease Ontology reflect the major expansions in KO to be more computational, portable (entification allows individual nodes to be extracted and used in combination with multiscale resources) and connected. Many techniques and methods used are not covered in KO textbooks. The interdisciplinary nature of KB development will be a worthwhile research area for the field of knowledge organization.