On the uniform stress/uniform stretch states of prestressed arteries

Xinyu Zhang, Alan J. Levy

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

This work examines the mechanics of the circumferentially prestressed N-layer artery, subject to axial tethering force and the internal pressure of blood, focusing on the uniform stretch state, the uniform circumferential stress states and the transitional states between them. Under increasing pressure the ith layer is shown to experience five distinct stages, two of which are the uniform stretch state and the uniform circumferential stress state. For arbitrary strain energy density, simple analytical expressions are presented for the stress distributions and the internal pressure at these specialized states. For the 1-layer, uniform tubular model of an artery without axial tethering force, the results coincide with those of Destrade et al. (2012). For the 2-layer composite tube, which models the mechanically significant medial and adventitial layers of large elastic arteries, numerical solutions are obtained employing two microstructurally based constitutive models for medial and adventitial arterial tissues, respectively. These results indicate that the uniform stretch state, the uniform circumferential stress state of the medial layer, and the uniform circumferential stress state of the adventitial layer occur at the diastolic blood pressure, the mean blood pressure, and the systolic blood pressure, respectively.

Original languageEnglish (US)
Article number110100
JournalJournal of Theoretical Biology
Volume486
DOIs
StatePublished - Feb 7 2020

Keywords

  • Composite tube
  • Finite elasticity
  • Mechanical homeostasis
  • Uniform stretch/stress states
  • Vascular mechanics

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

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