Noninvasive blood analysis by tissue modulated NIR Raman spectroscopy

Joseph Chaiken, William F. Finney, Paul E. Knudson, Karen P. Peterson, Charles M. Peterson, Xiaoke Yang, Ruth S. Weinstock

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We present tissue modulated Raman spectroscopy as a technique for noninvasively measuring the concentration of blood analytes in vivo. We present preliminary data used to determine the best methods for analyzing our data. These experiments provide additional proof that we are indeed able to obtain the spectra of human blood in vivo and noninvasively. We discuss differences between our spectra and spectra of bulk blood in vitro. We also discuss the variations between individuals and the impact of those variations on our noninvasive blood glucose measurements.

Original languageEnglish (US)
Pages (from-to)134-145
Number of pages12
JournalProceedings of SPIE - The International Society for Optical Engineering
Issue number1
StatePublished - Aug 23 2001

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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