Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses

Nathaniel Huebsch, Peter Loskill, Nikhil Deveshwar, C. Ian Spencer, Luke M. Judge, Mohammad A. Mandegar, Cade B. Fox, Tamer M A Mohamed, Zhen Ma, Anurag Mathur, Alice M. Sheehan, Annie Truong, Mike Saxton, Jennie Yoo, Deepak Srivastava, Tejal A. Desai, Po Lin So, Kevin E. Healy, Bruce R. Conklin

Research output: Contribution to journalArticle

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Abstract

Tissue engineering approaches have the potential to increase the physiologic relevance of human iPSderived cells, such as cardiomyocytes (iPS-CM). However, forming Engineered Heart Muscle (EHM) typically requires

Original languageEnglish (US)
Article number24726
JournalScientific Reports
Volume6
DOIs
StatePublished - Apr 20 2016
Externally publishedYes

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Cite this

Huebsch, N., Loskill, P., Deveshwar, N., Spencer, C. I., Judge, L. M., Mandegar, M. A., Fox, C. B., Mohamed, T. M. A., Ma, Z., Mathur, A., Sheehan, A. M., Truong, A., Saxton, M., Yoo, J., Srivastava, D., Desai, T. A., So, P. L., Healy, K. E., & Conklin, B. R. (2016). Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Scientific Reports, 6, [24726]. https://doi.org/10.1038/srep24726