Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect

Judith R. Millner; Tibor Palfai

doi:10.1016/0091-3057(75)90149-5

Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect

Judith R. Millner, Tibor Palfai

Department of Psychology

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

The effects of 40 mg/kg Metrazol on a conditioned saccharin aversion produced by LiCl were studied in two experiments. In Experiment 1, it was found that Metrazol administered 10 min before or after LiCl dis not impair conditioned aversion to saccharin. In Experiment 2, Metrazol was given 2 min before, 0 or 3 min after the administration of LiCl. Under these conditions, impairment did occur. It was concluded that Metrazol may impair conditioned taste aversion in a time-dependent manner. The present findings are discussed in terms of their relationship to ECS as an interfering agent and retroactive and proactive effects on the CS and/or the UCS.

Original language	English (US)
Pages (from-to)	201-204
Number of pages	4
Journal	Pharmacology, Biochemistry and Behavior
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/0091-3057(75)90149-5
State	Published - 1975

Keywords

Amnesia
Conditioned aversion
Lithium chloride
Metrazol

ASJC Scopus subject areas

Biochemistry
Toxicology
Pharmacology
Clinical Biochemistry
Biological Psychiatry
Behavioral Neuroscience

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abstract = "The effects of 40 mg/kg Metrazol on a conditioned saccharin aversion produced by LiCl were studied in two experiments. In Experiment 1, it was found that Metrazol administered 10 min before or after LiCl dis not impair conditioned aversion to saccharin. In Experiment 2, Metrazol was given 2 min before, 0 or 3 min after the administration of LiCl. Under these conditions, impairment did occur. It was concluded that Metrazol may impair conditioned taste aversion in a time-dependent manner. The present findings are discussed in terms of their relationship to ECS as an interfering agent and retroactive and proactive effects on the CS and/or the UCS.",

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AU - Millner, Judith R.

AU - Palfai, Tibor

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AB - The effects of 40 mg/kg Metrazol on a conditioned saccharin aversion produced by LiCl were studied in two experiments. In Experiment 1, it was found that Metrazol administered 10 min before or after LiCl dis not impair conditioned aversion to saccharin. In Experiment 2, Metrazol was given 2 min before, 0 or 3 min after the administration of LiCl. Under these conditions, impairment did occur. It was concluded that Metrazol may impair conditioned taste aversion in a time-dependent manner. The present findings are discussed in terms of their relationship to ECS as an interfering agent and retroactive and proactive effects on the CS and/or the UCS.

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KW - Conditioned aversion

KW - Lithium chloride

KW - Metrazol

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Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect

Abstract

Keywords

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