Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect

Judith R. Millner, Tibor Palfai

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

The effects of 40 mg/kg Metrazol on a conditioned saccharin aversion produced by LiCl were studied in two experiments. In Experiment 1, it was found that Metrazol administered 10 min before or after LiCl dis not impair conditioned aversion to saccharin. In Experiment 2, Metrazol was given 2 min before, 0 or 3 min after the administration of LiCl. Under these conditions, impairment did occur. It was concluded that Metrazol may impair conditioned taste aversion in a time-dependent manner. The present findings are discussed in terms of their relationship to ECS as an interfering agent and retroactive and proactive effects on the CS and/or the UCS.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Volume3
Issue number2
DOIs
StatePublished - Jan 1 1975

Keywords

  • Amnesia
  • Conditioned aversion
  • Lithium chloride
  • Metrazol

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Clinical Biochemistry
  • Biological Psychiatry
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect'. Together they form a unique fingerprint.

  • Cite this