Metrazol impairs conditioned aversion produced by LiCl: A time dependent effect

Judith R. Millner, Tibor Palfai

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


The effects of 40 mg/kg Metrazol on a conditioned saccharin aversion produced by LiCl were studied in two experiments. In Experiment 1, it was found that Metrazol administered 10 min before or after LiCl dis not impair conditioned aversion to saccharin. In Experiment 2, Metrazol was given 2 min before, 0 or 3 min after the administration of LiCl. Under these conditions, impairment did occur. It was concluded that Metrazol may impair conditioned taste aversion in a time-dependent manner. The present findings are discussed in terms of their relationship to ECS as an interfering agent and retroactive and proactive effects on the CS and/or the UCS.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Issue number2
StatePublished - 1975


  • Amnesia
  • Conditioned aversion
  • Lithium chloride
  • Metrazol

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Clinical Biochemistry
  • Biological Psychiatry
  • Behavioral Neuroscience


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