Method for Inhibiting the Formation of Set1 Family Core Complexes

Anamika Patel (Inventor), Michael Cosgrove (Inventor)

Research output: Patent

Abstract

Disclosed in this specification is a method for inhibiting the formation of vertebrate SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide.
Original languageEnglish (US)
Patent number8,715,678
StatePublished - Aug 8 2013

Fingerprint Dive into the research topics of 'Method for Inhibiting the Formation of Set1 Family Core Complexes'. Together they form a unique fingerprint.

  • Cite this

    Patel, A., & Cosgrove, M. (2013). Method for Inhibiting the Formation of Set1 Family Core Complexes. (Patent No. 8,715,678).