Memory storage impairment or retrieval failure: Pharmacologically distinguishable processes

Thomas J. Walsh, Tibor Palfai

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The effects of reserpine and syrosingopine on retention of a passive avoidance task in mice were investigated. Following repeated exposure to the training apparatus, the amnesia induced with syrosingopine could be reversed, the amnesia induced with reserpine could not. The amnesia produced by these agents was still evident 35 days following training. The results were discussed in terms of the effects of these drugs on memory consolidation and/or retrieval.

Original languageEnglish (US)
Pages (from-to)453-456
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Volume11
Issue number4
DOIs
StatePublished - Oct 1979

Keywords

  • Amnesia
  • Consolidation
  • Memory
  • Rauwolfia alkaloids
  • Retrieval

ASJC Scopus subject areas

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Clinical Biochemistry
  • Biological Psychiatry
  • Behavioral Neuroscience

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