Mechanisms in retrograde amnesia: a case for biogenic amines

Perry Kurtz, Tibor Palfai

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Research interpretations of the mechanisms by which various treatments produce retrograde amnesia are of three general types: (1) general modification of central nervous system excitability, (2) changes in the rate of brain protein or RNA synthesis, (3) alterations of brain neurotransmitter levels. Here, we review these interpretations and, within the framework of Kety's model, suggest that normal levels of biogenic amines during a critical period of memory storage may be essential for retention.

Original languageEnglish (US)
Pages (from-to)25-33
Number of pages9
JournalBiobehavioral Reviews
Issue number1
StatePublished - 1977


  • Amnesia
  • Biogenic amines
  • Catecholamines
  • ECS
  • Indole amines
  • Memory
  • Neurotransmitters
  • Reserpine
  • Retrograde amnesia
  • Serotonin

ASJC Scopus subject areas

  • General Neuroscience


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