Abstract
Elasticity is a key parameter in evaluating the structural stability of large polymeric molecules such as polysaccharides and polypeptides. The determination of the elastic parameters of complex biomolecules has been a long-standing challenge and terahertz spectroscopy is emerging as an ideal approach for such measurements. A new methodology is presented here, combining time-domain terahertz spectroscopy, X-ray diffraction, and solid-state density functional theory to achieve high-accuracy values for the Young's moduli of biopolymers. The capabilities are demonstrated by application of this method to crystalline poly-L-proline helices and other polypeptides.
Original language | English (US) |
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Title of host publication | 41st International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2016 |
Publisher | IEEE Computer Society |
Volume | 2016-November |
ISBN (Electronic) | 9781467384858 |
DOIs | |
State | Published - Nov 28 2016 |
Event | 41st International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2016 - Copenhagen, Denmark Duration: Sep 25 2016 → Sep 30 2016 |
Other
Other | 41st International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2016 |
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Country/Territory | Denmark |
City | Copenhagen |
Period | 9/25/16 → 9/30/16 |
ASJC Scopus subject areas
- Energy Engineering and Power Technology
- Electrical and Electronic Engineering