Language and literacy development in individuals with velo-cardio-facial syndrome

Kevin M. Antshel; Eileen Marrinan; Wendy R. Kates; Wanda Fremont; Robert J. Shprintzen

doi:10.1097/TLD.0b013e3181a72084

Language and literacy development in individuals with velo-cardio-facial syndrome

Kevin M. Antshel, Eileen Marrinan, Wendy R. Kates, Wanda Fremont, Robert J. Shprintzen

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion of chromosome 22q11.2. Although there is some variability, VCFS is associated with a characteristic physical, behavioral, and cognitive phenotype. This review article focuses on aspects of language and literacy development in VCFS, describing what is known and offering avenues for future research. The most consistently reported language and literacy findings in the VCFS population include reading, spelling, phonological processing, and auditory verbal rote memory abilities as areas of relative strength. Receptive language abilities are noted to be relatively stronger than expressive language abilities in individuals with VCFS. Speech disorders are very common in VCFS, and the most common compensatory articulation substitution in VCFS is the glottal stop.

Original language	English (US)
Pages (from-to)	170-186
Number of pages	17
Journal	Topics in Language Disorders
Volume	29
Issue number	2
DOIs	https://doi.org/10.1097/TLD.0b013e3181a72084
State	Published - Apr 2009
Externally published	Yes

Keywords

22q11.2 deletion syndrome
Genetic syndrome
Language
Literacy
VCFS

ASJC Scopus subject areas

Language and Linguistics
Linguistics and Language
Speech and Hearing

Access to Document

10.1097/TLD.0b013e3181a72084

Cite this

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title = "Language and literacy development in individuals with velo-cardio-facial syndrome",

abstract = "Velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion of chromosome 22q11.2. Although there is some variability, VCFS is associated with a characteristic physical, behavioral, and cognitive phenotype. This review article focuses on aspects of language and literacy development in VCFS, describing what is known and offering avenues for future research. The most consistently reported language and literacy findings in the VCFS population include reading, spelling, phonological processing, and auditory verbal rote memory abilities as areas of relative strength. Receptive language abilities are noted to be relatively stronger than expressive language abilities in individuals with VCFS. Speech disorders are very common in VCFS, and the most common compensatory articulation substitution in VCFS is the glottal stop.",

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AU - Marrinan, Eileen

AU - Kates, Wendy R.

AU - Fremont, Wanda

AU - Shprintzen, Robert J.

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Language and literacy development in individuals with velo-cardio-facial syndrome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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