Instrument for near infrared emission spectroscopic probing of human fingertips in vivo

Joseph Chaiken, Bin Deng, Rebecca J. Bussjager, George Shaheen, David Rice, Dave Stehlik, John Fayos

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We present instrumentation for probing of volar side fingertip capillary beds with free space coupled near infrared light while collecting Raman, Rayleigh, and Mie scattered light as well as fluorescence. Fingertip skin capillary beds are highly vascularized relative to other tissues and present a desirable target for noninvasive probing of blood. But human hands and fingers in particular are also highly idiosyncratic body parts requiring specific apparatus to allow careful and methodical spectoscopic probing. The apparatus includes means for precise and reproducible placement of the tissues relative to the optical aperture. Appropriate means are provided for applying and maintaining pressure to keep surface tissues immobile during experiments while obtaining the desired blood content and flow. Soft matter, e.g., skin, extrudes into the aperture in response to any applied pressure, e.g., to keep the tissue in registration with the optical system, so the position, contact area, pressure, and force are continuously measured and recorded to produce feedback for an actuator applying force and to discern the compliance of the test subject. The compliance strongly affects the reliability of the measurement and human factors must be adequately managed in the case of in vivo probing. The apparatus produces reproducible observations and measurements that allow consistent probing of the tissues of a wide range of skin types.

Original languageEnglish (US)
Article number034301
JournalReview of Scientific Instruments
Volume81
Issue number3
DOIs
StatePublished - 2010

Fingerprint

Tissue
Infrared radiation
Skin
Pressure
Compliance
blood
beds
Blood
apertures
Light
Optical Devices
Human engineering
Human Body
Optical systems
Fingers
Actuators
Hand
actuators
Fluorescence
Feedback

ASJC Scopus subject areas

  • Instrumentation
  • Medicine(all)

Cite this

Instrument for near infrared emission spectroscopic probing of human fingertips in vivo. / Chaiken, Joseph; Deng, Bin; Bussjager, Rebecca J.; Shaheen, George; Rice, David; Stehlik, Dave; Fayos, John.

In: Review of Scientific Instruments, Vol. 81, No. 3, 034301, 2010.

Research output: Contribution to journalArticle

Chaiken, Joseph ; Deng, Bin ; Bussjager, Rebecca J. ; Shaheen, George ; Rice, David ; Stehlik, Dave ; Fayos, John. / Instrument for near infrared emission spectroscopic probing of human fingertips in vivo. In: Review of Scientific Instruments. 2010 ; Vol. 81, No. 3.
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