Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist

David S. Hermelin; Jonathan D. Bortz; Robert Doyle

Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist

David S. Hermelin (Inventor), Jonathan D. Bortz (Inventor), Robert Doyle (Inventor)

Research output: Patent

Abstract

The present invention provides compositions and methods for lowering blood glucose. More specifically, the present invention provides compositions comprising a complex comprising IF and B12 conjugated to a peptide comprising a GLP-1 agonist. Advantageously, the composition may be delivered subcutaneously.

Original language	English (US)
State	Published - Nov 20 2017

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title = "Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist",

abstract = "The present invention provides compositions and methods for lowering blood glucose. More specifically, the present invention provides compositions comprising a complex comprising IF and B12 conjugated to a peptide comprising a GLP-1 agonist. Advantageously, the composition may be delivered subcutaneously.",

author = "Hermelin, {David S.} and Bortz, {Jonathan D.} and Robert Doyle",

year = "2017",

month = nov,

day = "20",

language = "English (US)",

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TY - PAT

T1 - Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist

AU - Hermelin, David S.

AU - Bortz, Jonathan D.

AU - Doyle, Robert

PY - 2017/11/20

Y1 - 2017/11/20

N2 - The present invention provides compositions and methods for lowering blood glucose. More specifically, the present invention provides compositions comprising a complex comprising IF and B12 conjugated to a peptide comprising a GLP-1 agonist. Advantageously, the composition may be delivered subcutaneously.

AB - The present invention provides compositions and methods for lowering blood glucose. More specifically, the present invention provides compositions comprising a complex comprising IF and B12 conjugated to a peptide comprising a GLP-1 agonist. Advantageously, the composition may be delivered subcutaneously.

M3 - Patent

ER -

Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist

Abstract

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