Improved Glycemic Control Using Intrinsic Factor Bound to a Vitamin B12 Conjugate of a Glucagon-Like Peptide-1 Receptor Agonist

David S. Hermelin (Inventor), Jonathan D. Bortz (Inventor), Robert Doyle (Inventor)

Research output: Patent


The present invention provides compositions and methods for lowering blood glucose. More specifically, the present invention provides compositions comprising a complex comprising IF and B12 conjugated to a peptide comprising a GLP-1 agonist. Advantageously, the composition may be delivered subcutaneously.
Original languageEnglish (US)
StatePublished - Nov 20 2017


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