@inproceedings{df619d51c4144c55b659a72ff9ebdc44,
title = "Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information",
abstract = "In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality",
keywords = "Explicit prior knowledge incorporation, Mesh-domain SPECT image reconstruction",
author = "Andrzej Krol and Levon Vogelsang and Yao Lu and Yuesheng Xu and Xiaofei Hu and Lixin Shen and David Feiglin and Edward Lipson",
year = "2009",
doi = "10.1117/12.813815",
language = "English (US)",
isbn = "9780819475091",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2009",
note = "Medical Imaging 2009: Physics of Medical Imaging ; Conference date: 09-02-2009 Through 12-02-2009",
}