Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information

Andrzej Krol, Levon Vogelsang, Yao Lu, Yuesheng Xu, Xiaofei Hu, Lixin Shen, David Feiglin, Edward Lipson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7258
DOIs
StatePublished - 2009
EventMedical Imaging 2009: Physics of Medical Imaging - Lake Buena Vista, FL, United States
Duration: Feb 9 2009Feb 12 2009

Other

OtherMedical Imaging 2009: Physics of Medical Imaging
CountryUnited States
CityLake Buena Vista, FL
Period2/9/092/12/09

Fingerprint

Atlases
Single-Photon Emission-Computed Tomography
mesh
Pixels
pixels
Image quality
registers
quantitative analysis
Noise
Chemical analysis
alternating current
attenuation
projection

Keywords

  • Explicit prior knowledge incorporation
  • Mesh-domain SPECT image reconstruction

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Krol, A., Vogelsang, L., Lu, Y., Xu, Y., Hu, X., Shen, L., ... Lipson, E. (2009). Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7258). [72585C] https://doi.org/10.1117/12.813815

Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information. / Krol, Andrzej; Vogelsang, Levon; Lu, Yao; Xu, Yuesheng; Hu, Xiaofei; Shen, Lixin; Feiglin, David; Lipson, Edward.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7258 2009. 72585C.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Krol, A, Vogelsang, L, Lu, Y, Xu, Y, Hu, X, Shen, L, Feiglin, D & Lipson, E 2009, Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7258, 72585C, Medical Imaging 2009: Physics of Medical Imaging, Lake Buena Vista, FL, United States, 2/9/09. https://doi.org/10.1117/12.813815
Krol A, Vogelsang L, Lu Y, Xu Y, Hu X, Shen L et al. Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7258. 2009. 72585C https://doi.org/10.1117/12.813815
Krol, Andrzej ; Vogelsang, Levon ; Lu, Yao ; Xu, Yuesheng ; Hu, Xiaofei ; Shen, Lixin ; Feiglin, David ; Lipson, Edward. / Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7258 2009.
@inproceedings{df619d51c4144c55b659a72ff9ebdc44,
title = "Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information",
abstract = "In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality",
keywords = "Explicit prior knowledge incorporation, Mesh-domain SPECT image reconstruction",
author = "Andrzej Krol and Levon Vogelsang and Yao Lu and Yuesheng Xu and Xiaofei Hu and Lixin Shen and David Feiglin and Edward Lipson",
year = "2009",
doi = "10.1117/12.813815",
language = "English (US)",
isbn = "9780819475091",
volume = "7258",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information

AU - Krol, Andrzej

AU - Vogelsang, Levon

AU - Lu, Yao

AU - Xu, Yuesheng

AU - Hu, Xiaofei

AU - Shen, Lixin

AU - Feiglin, David

AU - Lipson, Edward

PY - 2009

Y1 - 2009

N2 - In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality

AB - In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality

KW - Explicit prior knowledge incorporation

KW - Mesh-domain SPECT image reconstruction

UR - http://www.scopus.com/inward/record.url?scp=66749135923&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=66749135923&partnerID=8YFLogxK

U2 - 10.1117/12.813815

DO - 10.1117/12.813815

M3 - Conference contribution

AN - SCOPUS:66749135923

SN - 9780819475091

VL - 7258

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -