Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization

Ye Hongwei, Andrzej Krol, Edward D. Lipson, Lu Yao, Xu Yuesheng, Lee Wei, David H. Feiglin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

In order to improve tomographically reconstructed image quality, we have implemented a fully 3D reconstruction, using an ordered subsets expectation maximization (OSEM) algorithm for fan-beam collimator (FBC) SPECT, along with a volumetric system model-fan-volume system model (FVSM), a modified attenuation compensation, a 3D depth- and angle-dependent resolution and sensitivity correction, and a 3D total variation (TV) regularization. SPECT data were acquired in a 128×64 matrix, in 120 views with a circular orbit. The numerical Zubal brain phantom was used to simulate a FBC HMPAO Tc-99m brain SPECT scan, and a low noise and scatter-free projection dataset was obtained using the SimSET Monte Carlo package. A SPECT scan for a mini-Defrise phantom and brain HMPAO SPECT scans for five patients were acquired with a triple-head gamma camera (Triad 88) equipped with a low-energy high-resolution (LEHR) FBC. The reconstructed images, obtained using clinical filtered back projection (FBP), OSEM with a linelength system model (LLSM) and 3D TV regularization, and OSEM with FVSM and 3D TV regularization were quantitatively studied. Overall improvement in the image quality has been observed, including better axial and transaxial resolution, better integral uniformity, higher contrast-to-noise ration between the gray matter and the white matter, and better accuracy and lower bias in OSEM-FVSM, compared with OSEM-LLSM and clinical FBP.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6510
EditionPART 3
DOIs
StatePublished - 2007
EventMedical Imaging 2007: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2007Feb 22 2007

Other

OtherMedical Imaging 2007: Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/18/072/22/07

Fingerprint

Set theory
Fans
Brain
Image quality
Orbits
Cameras

Keywords

  • 3D total variation regularization
  • Fan-beam collimator
  • Fan-beam fully 3D reconstruction
  • HMPAO brain SPÉCT

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Hongwei, Y., Krol, A., Lipson, E. D., Yao, L., Yuesheng, X., Wei, L., & Feiglin, D. H. (2007). Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (PART 3 ed., Vol. 6510). [65104T] https://doi.org/10.1117/12.709560

Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization. / Hongwei, Ye; Krol, Andrzej; Lipson, Edward D.; Yao, Lu; Yuesheng, Xu; Wei, Lee; Feiglin, David H.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6510 PART 3. ed. 2007. 65104T.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hongwei, Y, Krol, A, Lipson, ED, Yao, L, Yuesheng, X, Wei, L & Feiglin, DH 2007, Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 3 edn, vol. 6510, 65104T, Medical Imaging 2007: Physics of Medical Imaging, San Diego, CA, United States, 2/18/07. https://doi.org/10.1117/12.709560
Hongwei Y, Krol A, Lipson ED, Yao L, Yuesheng X, Wei L et al. Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. PART 3 ed. Vol. 6510. 2007. 65104T https://doi.org/10.1117/12.709560
Hongwei, Ye ; Krol, Andrzej ; Lipson, Edward D. ; Yao, Lu ; Yuesheng, Xu ; Wei, Lee ; Feiglin, David H. / Implementation of a fully 3D system model for brain SPECT with fan-beam-collimator OSEM reconstruction with 3D total variation regularization. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6510 PART 3. ed. 2007.
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