Abstract
2‐(2′‐octenyl)succinic acid has been identified in urine samples from children investigated for a possible inherited metabolic disease. Its structural identification has been achieved by gas chromatography/mass spectrometry using both electron ionization and chemical ionization and by tandem mass spectrometry (MS/MS) using fast‐atom bombardment and high‐resolution electron‐ionization analyses of the molecular ion in a complex biological matrix. The localization of the double bond was obtained by interpretation of a unexpected rearrangement reaction occurring after dimethyl disulfide derivatization.
Original language | English (US) |
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Pages (from-to) | 170-172 |
Number of pages | 3 |
Journal | Rapid Communications in Mass Spectrometry |
Volume | 4 |
Issue number | 5 |
DOIs | |
State | Published - May 1990 |
Externally published | Yes |
ASJC Scopus subject areas
- Analytical Chemistry
- Spectroscopy
- Organic Chemistry